Optimize Your Custom Cell Culture Media

Successful development of cell and gene therapies is reliant on high-quality raw materials. Cell culture media is a vital material in this ecosystem as it is inexorably tied to cell performance. Nucleus Biologics’ intuitive tools for media formulation, customization, and optimization:

Enables Transparency

Each ingredient of your media is known and you own the formulas generated

Improves Outcomes

A single component or concentration change can have an impact 

Reduces Cost

Design and optimize media early, simplifying scale-up

Mitigates Risk

Avoid supply chain risk of sole sourcing 

We are uniquely positioned to help you bring your therapy to market faster.

Already have a Xuri™ Media Designer System account? 

Partnering to Bring You Transparent, cGMP, and Scalable Manufacture of Culture Media

Cytiva has partnered with Nucleus Biologics to bring you Xuri™ Media AI Guide and Xuri™ Media Designer System – state-of-the-art cell media design and supply based on Nucleus Biologics’ NB-AIR™ and NB-Lux™ platforms. These tools will accelerate the development of cell and gene therapies by allowing scientists to easily design optimized, high performance cell culture media – taking your formulations from bench to bioreactor. If a more white glove approach is required, rely on Nucleus Biologics’ expert formulation scientists who can work with you to provide end-to-end formulation services.

Already Know Your Formula, but Want to Customize Further?

Xuri™ Media Designer System

Configure your cell culture media and get a quote and lead time instantly.

Customize any aspect of media – ingredients, concentrations, lot sizes, volume, packaging configurations, testing, component grade, and more!

Need to Design Your Formula and Iterate Before You Scale?

Xuri™ Media AI Guide

Create custom formulations in minutes.

Design or refine media formulations based on peer-reviewed articles and community research and create a test matrix. Transfer your formula seamlessly to Xuri™ Media Designer System to configure and order.

Want End-to-End Expert Guidance?

Formulation Services

Work with our experts to design, configure, and test formulations that address all your critical quality attributes.

Configure and Order Media Instantly

Xuri™ Media Designer System is a unique online custom cell media configurator. Users can easily order their custom media or choose from one of the over 400 publicly available formulas and tailor any aspect of it to meet their unique specifications.

  • Configure components, concentrations, component grade, and testing options
  • Choose bags, bottles, or drums – separate bag configurator for ports and tubing choices
  • Select lot sizes from 2L to 2,000L
  • Manufacture in cGMP or research grade

Xuri™ Media Designer System provides total transparency on price, lead time, and components. Create media that is specifically customized for your process and reduce your time to market!

Design Your Formula in Minutes

Formulating custom media has traditionally been challenging and very time consuming due to the amount of data available to inform one’s design, produce desired effects, and improve cell performance.

Xuri™ Media AI Guide simplifies the process allowing users to create or refine a formulation based on peer-reviewed articles and community research in minutes. Leveraging a novel neural network, users of the platform can accentuate desired cellular critical quality attributes and receive multiple formulation recommendations from meta-analysis. Ownership of formulations remains with the user and formulas can be exported to Xuri™ Media Designer System when done for customization and ordering in small or large scale.

Expert-Guided Media Formulation

Work with our scientists to develop and deliver a complete formula that is custom designed to address all your critical quality attributes (CQAs). From start to finish, our team of experts will research components, design a formulation, manufacture media, test the media, and repeat until your custom media is optimized for your cell type to meet your project needs.

All designed formulations are owned by YOU and fully transparent – know every component and concentration – which ensures streamlined downstream steps for regulatory compliance and scalability.

Want to Learn More?

Have a question? Want to see a demo? Complete the form and one of our Customer Service Specialists will contact you within 24 hours.

Related Resources

On Demand Webinar:  Faster Media, Faster Outcomes

On Demand Webinar: Faster Media, Faster Outcomes

Introduction Full Webinar Recording Video Clip On Lead Times Video Clip On Cost Full Webinar Audio Full Webinar Transcript Introduction: This webinar will focus on understanding the time and cost of custom media and proprietary off-the-shelf media. We will cover such...

On Demand Webinar: Better Media, Better Outcomes

On Demand Webinar: Better Media, Better Outcomes

Introduction Webinar Recording Audio Transcript Introduction: Hear all about what is really in your cell culture media and why it matters. You will leave with an understanding of all the variables within your media and why controlling them is imperative to the...

On Demand Webinar: Path to Media Mastery 2

On Demand Webinar: Path to Media Mastery 2

Introduction Webinar Recording Audio Transcript Introduction: Our panelists, three prominent women in science, went from concept to custom media formulation to data in just over a month. Learn how you can design media in minutes with NB-AIR™ that performs better than...

On Demand Webinar: Path to Media Mastery

On Demand Webinar: Path to Media Mastery

Introduction Webinar Recording Audio Transcript Introduction: In Part 1 of this two-part series, three leading academic and industry scientists will demonstrate the Path to Media Mastery using NB-AIR™ to create custom media formulations to test with their protocols....