Buffer and Balanced Salt Solutions
Critical in almost every step of viral vector and gene therapy manufacturing processes as well as fundamental aspects of cell therapy process development, buffers are essential tools enabling optimization of vector stability, transfection efficiency, safety, targeting, and regulatory compliance.
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Any Bioprocessing Solution Made to Fit Your Needs
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Fully Customizable
Easily customize any aspect of buffer or balanced salt solutions, from pH levels and components to testing and packaging configurations.
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Transparent Process
Know every component and concentration. Your solution is designed and owned by you, making iteration and scale-up seamless.
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Premium Quality
Versatility at Every Stage: Any Serotype, Any Resin, Any System
Careful design of buffer solutions can optimize upstream and downstream processes – from cell culture buffers and media to downstream buffers to support filtration, chromatography, TFF just to name a few. We can customize and manufacture any buffer solution for any serotype that conforms to your specifications for all phases of cell and gene therapy development, clinical trials, and commercial manufacturing.
Enhance Flexibility as You Scale With Customizable Buffers
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Formulation
Specify your ingredients, concentrations, pH, and grade selection to receive a buffer solution that meets your application criteria.
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Volume
Get low-volume quantities of 500 mL to large volumes of up to 2,000L. Want to test an RUO sample of a lightly customized buffer solution?
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Packaging
Don’t let packaging define your process! Designed for flexibility, choose from vials, bottles, bags, drums, or any other bioprocessing container to fulfill your specific manufacturing needs.
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Testing and Manufacturing
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Your Partner of Choice
Why trust Nucleus Biologics? Simple, experience and expertise. We have formulated and manufactured buffers across the development spectrum for numerous industry collaborators. Develop optimal, individually-owned formulations and unlock the power of versatile buffer design with our innovative solutions tailored for any serotype at any stage. Utilize any resin or system to achieve unparalleled flexibility and efficiency in your processes.
Specifications
Pick Your Solution |
Pick your solution
|
Format |
Format Design and order custom solutions in volumes from 500 mL to 2,000L. |
Packaging |
Packaging
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Quality |
Quality GMP or RUO |
Testing Options |
Testing Options Sterility, Endotoxin, Mycoplasma, Osmolality, pH, Conductivity, Density, Bioburden Functional and stability testing services available; contact us for details |
Component Grade |
Component Grade USP, BP, EP, and JP grades available for many components |
Component Selection |
Component Selection Modify concentrations and components in the following categories: Additional uncategorized components are available |
Need Help?
Get in touch with our customer support team for any questions you may have.
Need Custom Media?
Partner with our scientist to design and optimize your cell culture media to achieve greater outcomes.
GMP Services
Resources
Explore our educational resources to learn how our cell culture media products and services can be a competitive advantage on your path to commercialization.
FAQs
What is a buffer solution?
A buffer is a solution consisting of a mixture of an acid and base. Buffer solutions can help cell cultures and liquids resist significant changes in pH levels.
What is a balanced salt solution?
A balanced salt solution is comprised of inorganic salts and serves to maintain pH and osmotic balance. A balanced salt solution is used when preparing complete cell culture medium and to wash or dilute cells.
Can I order concentrated stock balanced salt solutions?
Yes, you can order 10X stock of balanced salt solutions through NB-Lux.
What if I need a fully custom buffer or balanced salt solution or don't see the solution I need listed?
We can accommodate many fully custom requests. Contact us or reach out directly to your Technical Sales Specialist to discuss your custom project.
I already have a custom buffer / balanced salt solution but want to have it manufactured by Nucleus Biologics. Can I enter any solution, even a current formulation I am using, into NB-Lux™?
Yes, any formula can be inputted into NB-Lux and stored in our system. Once your components and concentrations are entered, you can order your buffer or balanced salt solution in your desired configuration and quality.
Are formulas that I input or create stored securely?
Yes. We ensure your data is stored securely with SSL encryption, multi-level authentication, and extensive firewall rules. Additionally, as with all services offered by Nucleus Biologics, your created and inputted formulas remain your intellectual property.