Krakatoa™ Benchtop Media Maker

Dispense cell culture media, buffers, and balanced salt solutions on your benchtop with Krakatoa, the world’s first benchtop media manufacturing system. Utilize compostable powder-filled pods and bring sustainability to your lab while you optimize and iterate your custom formulations. Krakatoa is manufactured by Stoic Bio.

Krakatoa™ Benchtop Media Maker

Manufacture Cell Culture Media on Your Benchtop

Media at Point-Of-Use

Benchtop solubilization provides fresh, cost-effective custom media, buffers, and balanced salts in minutes.

Sustainable Culture

Join the movement of labs striving for greener cell culture with biodegradable pods and fewer single-use plastics.

Sterile Media

UV sterilization and an integrated 0.2 micron filter ensure the level of quality necessary for even the most sensitive of applications.

User Friendly

Krakatoa is easy to use and includes an intuitive interface that makes media generation effortless.

Synergistic Media Solution

Formulate, customize, and manufacture media all within the Nucleus Biologics ecosystem, from iteration to scale-up.

Supply Chain Resilience

Mitigate risks associated with shipping delays, storage constraints, and temperature requirements with temperature stable, pod-based media.

Automated Media at the Touch of a Button

Krakatoa’s integrated UV-sterilization, intelligent sensing, and self-cleaning process ensure quality media and a smooth precise operation — a worry free experience.

Drive Performance and So Much More

Drive Optimized Performance

Iterate efficiently and identify optimized custom formulations in small volumes early in development. Plus, solubilization at point-of-use circumvents component degradation ensuring peak quality.

Lower Delivered Cost

Lightweight media pods lower shipping costs and nearly eliminate the need for refrigerated shipping. Custom media in smaller quantities for iteration decrease the upfront costs during testing phases, and reduces waste.

Scalable From Bench to Bioreactor

Formulations defined during early-stage iteration are stored in NB-Lux and can be scaled from pod to liquid in a bag or drum. Scale the production to match the demands of your commercialization efforts.

Reduce Environmental Footprint

Krakatoa’s lightweight biodegradable pods eliminate single-use PET bottles, decrease carbon emissions during shipping, and minimize the need for controlled temperature shipping.

Making Your Cell Culture Science Sustainable


Reduction in total greenhouse gas emissions per 500 mL of media produced


Reduction in transportation greenhouse gas emissions per 500 mL of media produced


Reduction in end-of-life greenhouse gas emissions per 500 mL of media produced

Media from Design to Delivery



Configure and order media, buffer, or balanced salt pods on NB-Lux. Convenient account features allow order tracking and storage of pertinent product information.



Solubilize your media on your benchtop. Insert your pod into Krakatoa and dispense media into the provided 500 mL glass bottle for fresh, sterile media within 30 minutes



Krakatoa pods are made of 96% recyclable and biodegradable material. Fill the provided bag with your used pods and send back to the device manufacturer, Stoic Bio, for recycling.

Determine Your Optimal Media While Reducing Plastic Waste

Sustainably iterate formulations while reducing plastic waste

Krakatoa pods are constructed with 96% recyclable and biodegradable material. Conveniently designed as a “plug and play” consumable, simply insert your custom designed pod and let Krakatoa do the work.

Documents and Downloads

Take a closer look at our helpful product information to learn how our cell culture media products and services can support and accelerate your groundbreaking research.

Krakatoa™ Product Note

Review the technical details, features, and benefits of the Krakatoa media maker.

LCA White Paper

Discover how Krakatoa reduces the environmental impact in this life cycle assessment.


Have a question? We’re here to help. If you don’t see your question, visit our FAQs page or contact us.

Where can I purchase cell culture media for the Krakatoa™ media maker?

Cell culture media, buffers, and balanced salt solutions for Krakatoa can be purchased on NB-Lux, Nucleus Biologics’ online customization and ordering platform. When on NB-Lux, select “Powder” in the “Format” section to purchase your media or reagent in a Krakatoa pod.

Krakatoa is manufactured by our sister company, Stoic Bio , and is distributed by Nucleus Biologics. Cell culture media and reagents for the Krakatoa media maker are manufactured by Nucleus Biologics.

What accessories are included with Krakatoa™?
With the purchase of any Krakatoa device, you will receive a starter kit that includes three glass bottles, a biodegradable bag holder, biodegradable bags to collect your pods after use, and a pod evacuation tool. To request additional bottles or bags, contact us.
Does the Krakatoa™ device require cleaning?

Krakatoa runs an internal self-cleaning cycle automatically after every pod run. No input is required from the user to initiate this sequence. External cleaning may be performed periodically in accordance with the guidelines in the user manual.

What type of warranty does Krakatoa™ come with?

Krakatoa comes with a limited 12-month warranty.

Once I start a pod run, do I need to be by the instrument during solubilization?

No. After inserting the pod and glass bottle, Krakatoa will run an automated pod run cycle and you do not need to be present for the solubilization stage of the pod run.

Contact Us

Ready to join the movement? Complete the form to be contacted by one of our Technical Sales Specialists.